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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e22cbb29f2fa67bba6bcc109fe8c929b18ffebef84f0295f391705729f41bb6' 
  AND token = 'Ln9bSBEJ1uJhFELm6thm9eNhFhAx0WSpELKz3eWRYrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}