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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8388f2209500cc36ceedf8c64af3d566f44fe40467ce9934e3e957a72938aeb3' 
  AND token = 'AV2ZQokrhqOb9dWcsPg+X7xiirNkHh+QdQNDR7I7u0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}