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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cf59a3e2352ec0060cf33796dae8b59f1d7779da2ac08d511a4cf60d1cc1bf9' 
  AND token = 'WKdAJGki2/+l9sItOmkmGz5M5+m4C3CWat/9Gp1Waas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}