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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b100e6a447cda581cf5c71050a448900f4e3be8d3e8c9ff5f860ce1d18b396' 
  AND token = '2uqBPMyl/YrMzOu2NuBS8g4a9St4LuFjXpIIRMJczEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}