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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd555bbb4133ffcdd11b34baf282b34eded5c373ea6e20592b86fd0722a5c4543' 
  AND token = 'EXp7kK7DFUSaO/rHAwA0G9/gClx8U+xLd2mj0lMNPJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}