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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c267e5ee562aa9fd5c227fd6a62492cd3d526323035e2cb49f8a12b2c60d7e97' 
  AND token = 'QFOKDXq8yyFtZW6bGXPmXmgslLD0L8cGSHiHt87JiRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}