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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b8f763e62332f935beb44a89c4c3bb7b350f4b0d88afd6f8cbb72225cefaf40' 
  AND token = 'd4GM0UBljwKLf98sNA2ZYV7OV4XHytrK6+xluJtNcUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}