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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4b85b8c002a43d64b3756ca771f59b25302a1adcb80206f798b1fd4ee44003' 
  AND token = '9PIT/R+wpXaGCT1b9SGGbADG6m6COeGZWQss6Wk5qg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}