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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75da957519d0d522120722462f7ecb9b2f5ab4e866b0cad8f526aa9e4d3bcfab' 
  AND token = 'TcGRWRfMbfq2ltNCwCAP/Kwt9vuxNg8w0G+tnXarIjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}