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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38917b274763a596f0cd4cab791a78ab7927b0ea6550c7dfaaebd5567555d958' 
  AND token = 'QRdthB/wYPGE1aX8+dwTd5kWWny1yP7Fx2eFs9xD/fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}