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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e55a70c6db9f3e36e801facfa3834a7801157da41051693df8d10a2c0dc39dd' 
  AND token = 'eRGonFdNosdEWFu5cjGeiHW5pQTc24JM9DnHxUu/3mE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}