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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d5a6e67adb1db2dc58c7a528798aa0049f841188ae8ab08269b8b60f8a700b' 
  AND token = 'CuSfl9yAqtYIT8dgzb6PQ+sGxZ5VyGxXmFgWDgSsXZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}