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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25433c7dfde0c5b1c7c761f36fbb19fc8b0fae0f8e16a122a0b032efa06fcdd5' 
  AND token = 'Qg/YAyoDlEiB3BjGtbaUcLDGPxgavqxCJ26VN3rri88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}