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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9105c5a30dc795783fd974592095e0b4d7546098f3fb154c0fdb38e419581ad9' 
  AND token = '8JKI1mBRg9KDiFkN5NhGJZWJx8wWMDWfdRj9k9iNZpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}