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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a2b17997af0afc836a913c41a580e55cebae6a0f80aa7c10db2665f839e9a0a' 
  AND token = 'zfvPGcp5UaMKny/XBaQhjlywGGzAarx+8a0yfW00RIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}