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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cee097e50d826aca2dca7af93910c38de22b323ee2a17551e68de6530d482cf' 
  AND token = 'y5a5+MKZGxul/VCmy/M1F2MezqsCb5dIwNXypScNlVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}