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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c88da21b9adfdecb4556222ed3031548bf1015c7ea0bac036b838ca7e3041cb' 
  AND token = 'fwTDs1a8Q5HuodK6/qz/AoZUB5UyNqDtmDTIVr3o4bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}