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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '099b6b387452414068e46e1dc779eb268a1e89f9134c89989ec7131caeefac01' 
  AND token = 'e28JyOdAiEF1S7FHLuFPpw+5WodV4aWgcShSzITfqYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}