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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18dddda645d5313bbe520766c244c0d9256dc3dd2694de6d242e059fc07c519f' 
  AND token = 'jhRSlumGvke6+6mqCR4J1XVNdmO46sCA8xW/GSJZ+0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}