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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7ef807e056ce86a96357a7c4d275d1153ac04a33107f7042bae60c78712447c' 
  AND token = 'FotxlyEwpjQr8gqZepl5GYApbzHH3Hg9+bbEe2aFuzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}