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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '465393cc52fd6bd68dc4be2828a6665e85a2ee67f3cd37f708c053a1a03aafe1' 
  AND token = 'lHM583ZZcKwc43qRO0blyANKn2EvbF8uzmCugCmFEdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}