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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d8f94418ee76ea7136d82d2570b28b15a844e6184ca46c081178373e93ddbf' 
  AND token = 'HFG7k3t3RrUAVxKdXJPI3sr3DJE698rv/4PwEwrRXho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}