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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b15c04c5f4e52fd4829515e37fd2f99820b18740f2417a9fbdca8c8c3dbc6361' 
  AND token = 'WanrtIwf1FUE8NdbDFDKv28rNRryaw4IuBmy7vSauvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}