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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e69f709cf762c87a770c4363735a51ad20e7b7b73b1edda923d00ca0dfb0c12' 
  AND token = 'o2RRO57YCBEMtjmRuzDXAyiVKm+GCKic6XzvSaIHkxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}