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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c4e10f1e8e8d428d0b1cbd9fcb9899f269817d848f9d09d39e7b0e2269053f9' 
  AND token = 'toDt9UuVrQGZnrHZh5HW5+acflRIl3jVzwdQjQtzZBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}