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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16cf1a080c12ee0eb9b43e17f1c92c660655edb34313d44916a5dfc3e6dab9ea' 
  AND token = '/DfDYswLsEX3JEMBYlTQTyFhCmtrTJPTksF4rWoVdd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}