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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fb4623c141c853f4af4cc00a789ff51e7ab51dfa5d98f6f0a3685e724e157a0' 
  AND token = 'yHcha/l075ToGnCO6wqTMnFswgje/OGpakGEJogj2ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}