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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff2aff6e2f6578ed7a0b5ff3b1faffdc0124c26d48a5ae16744401260c2189b8' 
  AND token = 'G5lVvAFemmoryIjjYpoHaKrQ/Y7cKk5+fmkAADkAzhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}