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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea53877d9cb67969c5c245c0def10edc143dfbb0c647815ac9c4be7153a4b8a5' 
  AND token = 'U9iXSFW+cPNVGNDbrWi58I7y2RHw9zPvtpBmjPMWanw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}