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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64078a7e97cc743cc719b229ba76d716b7d08d6ce7ceac3e6a9afa8220e7cd5b' 
  AND token = 'wdsnuhLlMhLVsTGT1Fw8X8040A9+F8dukXG/TcHVoeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}