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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a6ae1035fd0b15116244b9e3b806143420b0f6271fe981fe5a7646af0b9980e' 
  AND token = 'Gfh5WroAjAjRWZwt4EvpEgEX9KN2ioPcOa54+AiSOAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}