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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a7b1c214a453636cd2d09a25aa19a74e98d27e7d9d020fd3fac03288a899b7' 
  AND token = 'G8KY27PelbraA43jbFmpbWY1vpJCuiJ+0OL3HaTWGxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}