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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f75ec54f8baf424f5a67060fd2d4e2af06513beb6bb7a5e642784d6345f6aa2a' 
  AND token = 'hSyAMpYusuNCtlj1kL7mYKtECsjkM69xF8NgsOaz+FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}