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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0753eee5d753500aab2fc096008a723dd9e9a195fe3d77dcf0407d3b2ee1ab2d' 
  AND token = '7w5a4dH1RsgkqxYagfrjP41qlj5GCvDSCd0V50Jw3Ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}