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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc9bed779049a44da2c34752aa35f205a48c7dbf4e8766bf3f7e7eeb28305554' 
  AND token = 'TWRDbOenXqLOpIba2gvJoVQD8WyxiwEn3orLaYv85Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}