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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6aa146b6570f0fa7fe4418d81371794a17226a263843b570a692bdfad3601dee' 
  AND token = '3V2LTWnDbMtGIsnDo1Bpf617oZ0QFOOMDC3fvIq1xvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}