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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fb816db300561ddde21d4d556e63c39367a209f9d72c9ce647a5d71c589c2fa' 
  AND token = '9enXFrqgfcfiETr77xXubQXTfBBQQRZRVA4k/BwUo0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}