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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a6e1a9f29cd193016b26329b26391f0c56905ed9611bd02a4f82ca8a23bf0e' 
  AND token = '+0wH30siasQ+j/qrYrBDvKpcasPz9JkzvEdq8wzbypM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}