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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b50522d61f3d2a46ee98f689521f89c71517dfa6bba0de4155c371ad680ad9' 
  AND token = 'UAj28NfDYkUy0ov1wVXN4BfxrCn3C8A6Ys3F0vCrP3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}