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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b149963cc66866f89a42ac4e937188423e6b99d9c1a3b9920d443ad9a323e6e3' 
  AND token = '1N0efq5xeiHupgrOv1YGYmH377+DINsXyTEXwzpVJXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}