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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d59139647714dd6cd63947fe3546ca6e0fd13bf74ca54e2df1e9d4a01bc7639' 
  AND token = 'cQDb+4xg5QAid9wrdeDgAoL6ZvE7/f1d9QgTo7xtJRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}