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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e745129c734e2bdd9ccbba580caed7216f4c5a1c7def5b741827cc6a43c946' 
  AND token = '5J6keD4CNUU39b3R50pVtt1CV7ksYn29wNha1na1B44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}