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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ef85238c3a41b8e911dd275bec41d4a6a727b7204cc5629d03427480a97ab57' 
  AND token = 'QZnWmz3Bt/VMcJidX0C+590npuT+DxFNAarhwS9i/Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}