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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1f3a045cf6e442101ac33117ce2effc137590a1219d7feadfc2e2bfe48f4ee' 
  AND token = 'So49rBn47z60iX2TeAz+rjPvskRs9vfhmaGEvpFksyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}