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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34543b3cbc003dd57824791c0e6b0a1c1271a47413b8106e334a4c3b1d2d50c9' 
  AND token = 'WQlW0KU+TOx4PQ+57kUQK1evlAABWbs7zt0tPnZNDPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}