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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd760d8536a80790f0513373156a2c5338ae72191e6df3038f39f9b5fe80bb4f6' 
  AND token = 'Vb6cOVxV+Ob3KD/21nxlcj3vWfvhc3ADcmb5uIMt7ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}