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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '718b39f192bfab17eaaa17018ca2975bfa94a2b22cdb1d517e0d5c71432daf4d' 
  AND token = '5z92ELNu5qgHtG9XGBQ8FSDCJ9DPT/HefT9bzOJxBbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}