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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '479bb9b595ace8dc0679720be67aba44c6cf66043b73de650ad7ffaff07e8a8a' 
  AND token = 'Q8HMtYsqvtgXX1FbD/RW4by9bWYDuT2T5AV3zPhANX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}