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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2195b0856db0e53f379ced09b26b578c0a2eff74f85643cdeba62eb65eb4f895' 
  AND token = '9mv9ZwL1axxPsA3R0BeAyTp61vW4h5mO0KWv8jbv5ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}