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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f29471bac1fa3a8d0b790a06e2fdb2f0b85229da55161f7562598355764c4dc' 
  AND token = 'I65jtJs6tw8G2ZquQ0c4734LKVMLKfPZQH1MG8tUpMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}